【作者单位】1 Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, People’s Republic of China.; 2 Department of biology, Chongqing University of Science and Technology, Chongqing 401331, People’s Republic of China.; 3 Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), School of Life Sciences, Southwest University, Chongqing 400715, People’s Republic of China.; 4 Agricultural and Animal Husbandry College, Tibet University, Linzhi of Tibet 860000, People’s Republic of China.; 5 Chongqing Academy of Chinese Materia Medica, Chongqing 400065, People’s Republic of China.; 6 Institute of Plant and Microbial Biology, Academia Sinica, Taipei 11529, Taiwan.
【摘要】 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase (HDR, EC 1.17.1.2) catalyzes the last reaction of the methylerythritol phosphate (MEP) pathway. The full-length cDNA sequence of HDR was cloned and characterized from terpenoid-indole-alkaloid-...