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Evolutionary significance of selected EDAR variants in Tibetan high-altitude adaptations

  • 【作者】Shao, J.,Raza, M.S.,Zhuoma, B.,Zeng, C.
  • 【作者单位】a CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 100101, China; b University of Chinese Academy of Sciences, Beijing, 100049, China; c The Innovation Center of Excellence on Science and Education of Life Sciences, Chinese Academy of Sciences, Beijing, 100049, China; d Collaborative Innovation Center of Genetics and Development, Shanghai, 200438, China; e Medical College of Tibet University, Lhasa, 850002, China
  • 【年份】2018
  • 【卷号】Vol.61 No.1
  • 【页码】68-78
  • 【ISSN】1674-7305
  • 【关键词】EDAR high altitude adaptation Tibetan 
  • 【摘要】 Humans have been exposed to many environmental challenges since their evolutionary origins in Africa and subsequent migrations to the rest of the world. A severe environmental challenge to human migrants was hypoxia caused by low barometric oxygen pr...
  • 【文献类型】 期刊
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