Proteomic Analysis and NIR-II Imaging of MCM2 Protein in Hepatocellular Carcinoma.

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【作者】Jing Yang，Qi Xie，Hui Zhou，Lei Chang，Wei Wei，Yin Wang，Hong Li，Zixin Deng，Yuling Xiao，Junzhu Wu，Ping Xu，Xuechuan Hong
【作者单位】State Key Laboratory of Virology, Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) and Zhongnan Hospital of Wuhan University , Wuhan University School of Pharmaceutical Sciences , Wuhan 430071 , China. State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), Beijing Proteome Research Center , Beijing Institute of Lifeomics , Beijing 102206 , China. Center for Experimental Basic Medical Education, School of Basic Medical Sciences, Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals and Hubei Provincial Key Laboratory of Developmentally Originated Disease , Wuhan University , Wuhan 430071 , China. Pathology Department , Binzhou Medical University Hospital , Binzhou 256600 , China. Anhui Medical University , Hefei 230032 , China. Medical College , Tibet University , Lasa 850000 , China.
【年份】2018
【卷号】Vol.17 No.7
【页码】2428-2439
【ISSN】1535-3907
【关键词】NIR-II imaging minichromosome maintenance proteins proteomics targets
【摘要】 Targeted therapy of hepatocellular carcinoma is essential for improved therapies. Therefore, identification of key targets specifically to HCC is an urgent requirement. Herein, an iTRAQ quantitative proteomic approach was employed to identify differ...
【文献类型】期刊