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Upregulation of miR-520c-3p via hepatitis B virus drives hepatocellular migration and invasion by the PTEN/AKT/NF-κB axis

  • 【获取途径】 OA资源
  • 【作者】Yang Liu,Jingwen Wang,Jianwen Chen,Shaoshuai Wu,Xianhuang Zeng,Qiushuang Xiong,Yandan Guo,Junwei Sun,Feifei Song,Jiaqi Xu,Sen Yuan,Chuang Li,Yuan He,Ming Wang,Lang Chen,Yun-Bo Shi,Mingxiong Guo,Deyin Guo,Guihong Sun
  • 【作者单位】1Taikang Medical School (School of Basic Medical Sciences), Wuhan University, Wuhan 430071, Hubei, P.R. China;2These authors contributed equally;3Department of Hepatic & Biliary & Pancreatic Surgery, Hubei Cancer Hospital, Affiliated Hubei Cancer Hospital of Huazhong University of Science and Technology, Wuhan 430079, Hubei, P.R. China;4Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan 430072, Hubei, P.R. China;5Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, P.R. China;6Section on Molecular Morphogenesis, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, MD 20892, USA;7Ecological Research Center, College of Science, Tibet University, Lhasa 850012, Tibet, P.R. China;8School of Medicine, Sun Yat-Sen University, Guangzhou 510000, Guangdong, P.R. China;9Hubei Provincial Key Laboratory of Allergy and Immunology, Wuhan 430071, Hubei, P.R. China
  • 【年份】2022
  • 【卷号】Vol.29
  • 【页码】47-63
  • 【ISSN】2162-2531
  • 【关键词】MT: non-coding RNAs hepatocellular carcinoma miR-520c-3p HBV/HBx PTEN migration and invasion NF-κB 
  • 【摘要】 Hepatitis B virus is a major risk factor for the development and progression of hepatocellular carcinoma . It has been reported that viral infection can interfere with the expression of cellular microRNA to affect oncogenesis. In this study, we sho...
  • 【文献类型】 期刊
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