Malus toringoides Hughes Ameliorates Nonalcoholic Fatty Liver Disease with Diabetes via Downregulation of SREBP-1c and the NF- κ B Pathway In Vivo and In Vitro
【作者】Mi Xie, Liying Gao, Zhiming Liu, Ruiying Yuan, Dongzhi Zhuoma, Dikye Tsering, Yuefei Wang, Shan Huang, Bin Li
【作者单位】Affiliations 1 Department of Pharmacy, Key Laboratory of Pharmaceutical Research for Metabolic Diseases, Qingdao University of Science & Technology, Qingdao, China. 2 College of Pharmacy, Chosun University, Gwangju, Korea. 3 Center of Tibetan Studies (Everest Research Institute), Tibet University, Lhasa, China. 4 Department of Pharmacy, University of Tibetan Medicine, Lhasa, China. 5 Tianjin Key Laboratory of TCM Chemistry and Analysis, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
【摘要】 Diabetic patients are more prone to developing nonalcoholic fatty liver disease compared with healthy people. As a plant homologous to both medicine and food, Malus toringoides Hughes has been used as an intervention for both NAFLD and diabetes. Ho...