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Wip1 contributes to the adaptation of HepG2 human liver cancer cells to stress hormone-induced DNA damage

  • 【作者】Gaoxiang Li,Yazhi Qian,Yuzhu Chen,Mingyue Cao,Xiaozhou Yang,Dexin Kong,Guiping Wang,Haiyan An,Nan Yang,Wei Huang,Yanyong Liu
  • 【作者单位】Affiliations 1 Department of Pharmacology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, Beijing 100005, P.R. China. 2 Medical College, Tibet University, Lhasa, Tibet Autonomous Region 850000, P.R. China. 3 Department of Anesthesiology, Peking University People's Hospital, Beijing 100044, P.R. China.
  • 【年份】2022
  • 【卷号】Vol.25 No.1
  • 【页码】31
  • 【ISSN】1792-1082
  • 【关键词】PPM1D Wip1 adaptive DNA damage liver cancer stress hormone. 
  • 【摘要】 Numerous studies have shown that the release of stress hormones resulting from repeated exposure to chronic psychological stress increases DNA damage and promotes tumorigenesis. However, the mechanisms that enable cancerous cells adapt to stress horm...
  • 【文献类型】 期刊
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