Engineering and Characterization of an Artificial Drug-carrying Vesicles Nanoplatform for Enhanced Specifically Targeted Therapy of Glioblastoma

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【作者】Jiaqi Liu, Yuting Sun, Xianhuang Zeng, Yang Liu, Chaozhi Liu, Ying Zhou, Yueguang Liu, Guihong Sun, Mingxiong Guo
【作者单位】Affiliations ¹ Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei, 430072, P. R. China. ² Taikang Medical School (School of Basic Medical Sciences), Wuhan University, Wuhan, Hubei, 430071, P. R. China. ³ Neuregen therapeutics (Suzhou) Co. Ltd, Suzhou, Jiangsu, 215200, P. R. China. ⁴ Hubei Provincial Key Laboratory of Allergy and Immunology, Wuhan, Hubei, 430071, P. R. China. ⁵ School of Ecology and Environment, Tibet University, Lhasa, Tibet, 850000, P. R. China.
【年份】2023
【页码】e2303660
【ISSN】1521-4095
【关键词】blood-brain barrier engineered artificial vesicles glioblastoma multiforme.
【摘要】 Glioblastoma multiforme treatment is hindered by complex pathologies and the need to cross the blood-brain barrier during drug delivery. Although exosomes have great potential for GBM treatment, these alone cannot fully meet the therapeutic require...
【文献类型】期刊