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Isovanillic acid protects mice against Staphylococcus aureus by targeting vWbp and Coa

  • 【获取途径】 OA资源
  • 【作者】Xiangqian Chen, Chunjie Hu, Zunhua Shu, Xingye Wang, Yicheng Zhao, Wu Song, Xiaoyu Chen, Mengli Jin, Yang Xiu, Xuerui Guo, Xiangri Kong, Yijing Jiang, Jiyu Guan, Lanzi Gongga, Li Wang, Bingmei Wang
  • 【作者单位】Affiliations 1 Changchun University of Chinese Medicine, Changchun, 130117, China. 2 Proctology Department, Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, 130021, China. 3 The Third Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, 130118, China. 4 Center for Pathogen Biology & Infectious Diseases, Key Laboratory of Organ Regeneration & Transplantation of the Ministry of Education, The First Hospital of Jilin University, Changchun,130021, China. 5 School of Pharmacy, Jilin University, Changchun, 130021, China. 6 Key Laboratory of Zoonosis, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, 130062, China. 7 Tibet University Medical College, Tibet, 850000, China.
  • 【年份】2023
  • 【ISSN】1746-0921
  • 【关键词】Staphylococcus aureus coagulase isovanillic acid pneumonia von Willebrand factor binding protein. 
  • 【摘要】 Aim: Our primary objective was to investigate the protective effects and mechanisms of isovanillic acid in mice infected with Staphylococcus aureus Newman. Methods: In vitro coagulation assays were used to validate vWbp and Coa as inhibitory targets ...
  • 【文献类型】 期刊
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