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TBK1-stabilized ZNF268a recruits SETD4 to methylate TBK1 for efficient interferon signaling

  • 【获取途径】 OA资源
  • 【作者】Yi Liu,Wei Yin,Xianhuang Zeng,Jinhao Fan,Chaozhi Liu,Mingyu Gao,Zan Huang,Guihong Sun,Mingxiong Guo
  • 【作者单位】1Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan 430072, Hubei, P.R. China;2Taikang Medical School (School of Basic Medical Sciences), Wuhan University, Wuhan 430071, Hubei, P.R. China;3School of Ecology and Environment, Key Laboratory of Biodiversity and Environment on the Qinghai-Tibetan Plateau of Ministry of Education, Tibet University, Lhasa 850000, Tibet, P.R. China;4Hubei Provincial Key Laboratory of Allergy and Immunology, Wuhan 430071, Hubei, P.R. China
  • 【年份】2023
  • 【页码】105428
  • 【ISSN】0021-9258
  • 【关键词】ZNF268a TBK1 methylation SETD4 Virus-induced interferon signaling 
  • 【摘要】 Sufficient activation of interferon signaling is critical for the host to fight against invading viruses, in which post-translational modifications have been demonstrated to play a pivotal role. Here, we demonstrate that human KRAB-zinc finger protei...
  • 【文献类型】 期刊
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