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Pseudomonas aeruginosa regulator PvrA binds simultaneously to multiple pseudo-palindromic sites for efficient transcription activation

  • 【作者】Yibo Zhu, Bingnan Luo, Xingyu Mou, Yingjie Song, Yonghong Zhou, Yongbo Luo, Bo Sun, Youfu Luo, Hong Tang, Zhaoming Su, Rui Bao
  • 【作者单位】Affiliations 1 Center of Infectious Diseases, Division of Infectious Diseases in State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China. 2 Accurate Biotechnology (Hunan) Co., Ltd, Changsha, 410006, China. 3 College of Life Science, Sichuan Normal University, Chengdu, 610101, China. 4 Key Laboratory of Biodiversity and Environment on the Qinghai-Tibetan Plateau, Ministry of Education, School of Ecology and Environment, Tibet University, Lhasa, 850000, China. 5 Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai, 201210, China. 6 Center of Infectious Diseases, Division of Infectious Diseases in State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China. htang6198@hotmail.com. 7 Center of Infectious Diseases, Division of Infectious Diseases in State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China. zsu@scu.edu.cn. 8 Department of Geriatrics and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, China. zsu@scu.edu.cn. 9 Center of Infectious Diseases, Division of Infectious Diseases in State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China. baorui@scu.edu.cn.
  • 【年份】2023
  • 【ISSN】1869-1889
  • 【关键词】Pseudomonas aeruginosa TetR protein- structure transcription regulator virulence. 
  • 【摘要】 Tetracycline repressor family regulators are the largest group of DNA-binding transcription factors and are widely distributed in bacteria and archaea. TFRs play vital roles in controlling the expression of various genes and regulating diverse phys...
  • 【文献类型】 期刊
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