【作者单位】Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University) '(1)' ; Ministry of Education; Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong [2] ; Yantai University [3] ; Yantai 264005 [4] ; China. Electronic address: hongbowangyt@gmail.com. [5] ; State Key Laboratory of Virology [6] ; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) and Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals [7] ; Wuhan University School of Pharmaceutical Sciences [8] ; Wuhan 430071 [9] ; China. [10] ; Department of Integrative Biology and Pharmacology [11] ; McGovern Medical School [12] ; The University of Texas Health Science Center at Houston [13] ; Houston [14] ; TX 77030 [15] ; USA. [16] ; Innovation Center for Traditional Tibetan Medicine Modernization and Quality Control [17] ; Medical College [18] ; Department of Chemistry and Environmental Science [19] ; School of Science [20] ; Tibet University [21] ; Lhasa 850000 [22] ; China; Innovation Center for Traditional Tibetan Medicine Modernization and Quality Control [23] ; China. Electronic address: xhy78@whu.edu.cn. [24] ; USA. Electronic address: michael.x.zhu@uth.tmc.edu. [25]
【页码】107497
【关键词】Calcium signaling Drug discovery Heterotrimeric G proteins Nonselective cation channels Phospholipase C Receptor-operated channels
【摘要】 Transient receptor potential canonical channels constitute a group of receptor-operated calcium-permeable nonselective cation channels of the TRP superfamily. The seven mammalian TRPC members, which can be further divided into four subgroups based ...
