【作者】Hui-Hui Zhang, Chao Li, Jian-Wei Ren, Lian Liu, Xue-Hua Du, Jie Gao, Tao Liu, Shang-Ze Li
【作者单位】Affiliations 1 Department of Laboratory Medicine, Hunan Normal University School of Medicine, Changsha, Hunan, 410013, China. 2 Key Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province, Hunan Normal University School of Medicine, Changsha, Hunan, 410013, China. 3 Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei, 430072, China. 4 Tibet University Medical College, Lhasa, Tibet, 850000, China. 5 Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, 430071, China. 6 School of Medicine, Chongqing University, Chongqing, 400030, China.
【年份】2021
【ISSN】1349-7006
【关键词】ATF6 OTUB1 UPR bladder cancer deubiquitination.
【摘要】 The unfolded protein response plays an important role in carcinogenesis, but the functional role and mechanism of UPR-associated bladder carcinogenesis remain to be characterized. Upon UPR activation, ATF6α is activated to upregulate the transcripti...
