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Evolutionary significance of selected EDAR variants in Tibetan high-altitude adaptations.

  • 【作者】Shao J,Raza MS,Zhuoma B,Zeng C.
  • 【DOI】10.1007/s11427-016-9045-7
  • 【作者单位】1 CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 100101, China. 2 University of Chinese Academy of Sciences, Beijing, 100049, China. 3 Medical College of Tibet University, Lhasa, 850002, China. 4 CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 100101, China. czeng@big.ac.cn. 5 University of Chinese Academy of Sciences, Beijing, 100049, China. czeng@big.ac.cn. 6 The Innovation Center of Excellence on Science and Education of Life Sciences, Chinese Academy of Sciences, Beijing, 100049, China. czeng@big.ac.cn. 7 Collaborative Innovation Center of Genetics and Development, Shanghai, 200438, China. czeng@big.ac.cn.
  • 【年份】2017
  • 【ISSN】1674-7305
  • 【关键词】EDAR Tibetan high altitude adaptation 
  • 【摘要】 Humans have been exposed to many environmental challenges since their evolutionary origins in Africa and subsequent migrations to the rest of the world. A severe environmental challenge to human migrants was hypoxia caused by low barometric oxygen pr...
  • 【文献类型】 期刊
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