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Self-organizing map of gene regulatory networks for cell phenotypes during reprogramming

  • 【作者】Leping Zhang,Yufang Zheng,Dongfang Li,Yang Zhong,
  • 【作者单位】; 1 Second Mil Med Univ, Coll Basic Med Sci, Shanghai 200433, Peoples R China        Second Military Medical University ; 2 Fudan Univ, Sch Life Sci, Shanghai 200433, Peoples R China        Fudan University ; 3 Tibet Univ, Inst Biodivers Sci & Geobiol, Lhasa 850000, Peoples R China        Tibet University
  • 【年份】2011
  • 【卷号】Vol.35 No.4
  • 【页码】211-217
  • 【ISSN】1476-9271;1476-928X
  • 【关键词】Self-organizing map Gene regulatory network Cell phenotype Reprogramming 
  • 【摘要】 The induced pluripotent cells are derived from somatic cells by reprogramming their genetic profiles. Such a process requires coordinated dynamic expression of hundreds of genes and proteins. As both deterministic and stochastic elements control the...
  • 【文献类型】 期刊
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