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A natural phenylpropionate derivative from Mirabilis himalaica inhibits cell proliferation and induces apoptosis in HepG2 cells

  • 【作者】LingHu Lang,Shunqin Zhu,Haoxing Zhang,Panpan Yang,Haixia Fan,Shanlin Li,Zhihua Liao,Xiaozhong Lan,Hongjuan Cui,Min Chen
  • 【DOI】10.1016/j.bmcl.2014.10.011
  • 【作者单位】a Key Laboratory on Luminescence and Real-Time Analysis (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China b State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400715, China c School of Life Sciences, Southwest University, Chongqing 400715, China d Tibetan Collaborative Innovation Center of Agricultural and Animal Husbandry Resources, Agriculture and Animal Husbandry College, Tibet University, Nyingchi, Tibet 860000, China
  • 【年份】2014
  • 【卷号】Vol.24 No.23
  • 【页码】5484-5488
  • 【ISSN】0960-894X
  • 【关键词】Mirabilis himalaica Cell proliferation Cell cycle Apoptosis HepG2 
  • 【摘要】 Bioactivity-guided study led to the isolation of a natural phenylpropionate derivative, (E)-3-(4-hydroxy-2-methoxyphenyl)-propenoic acid 4-hydroxy-3-methoxyphenyl ester from the roots of Mirabilis himalaica. Cellular analysis showed that compound 1 s...
  • 【文献类型】 期刊
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