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Self-organizing map of gene regulatory networks for cell phenotypes during reprogramming

  • 【作者】Leping Zhang,Yufang Zheng,Dongfang Li and Yang Zhong
  • 【DOI】10.1016/j.compbiolchem.2011.05.002
  • 【作者单位】a School of Life Sciences, Fudan University, Shanghai 200433, People's Republic of China b College of Basic Medical Sciences, Second Military Medical University, Shanghai 200433, People's Republic of China c Institute of Biodiversity Science and Geobiology, Tibet University, Lhasa 850000, People's Republic of China
  • 【年份】2011
  • 【卷号】Vol.35 No.4
  • 【页码】211-217
  • 【ISSN】1476-9271
  • 【关键词】Self-organizing map Gene regulatory network Cell phenotype Reprogramming 
  • 【摘要】 The induced pluripotent cells (iPSCs) are derived from somatic cells by reprogramming their genetic profiles. Such a process requires coordinated dynamic expression of hundreds of genes and proteins. As both deterministic and stochastic elements cont...
  • 【文献类型】 期刊
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