The c-Terminal effector Domain of non-structural Protein 1 of influenza a Virus Blocks IFN-beta Production by Targeting TnF receptor-associated Factor 3

分享到

【获取途径】 OA资源
【作者】Qian, Wei，Wei, Xiaoqin，Guo, Kelei
【作者单位】; 1 Huazhong Agr Univ, State Key Lab Agr Microbiol, Wuhan, Peoples R China ; 2 Huazhong Agr Univ, Dept Prevent Vet Med, Coll Anim Sci Med, Wuhan, Peoples R China ; 3 Tibet Univ, Coll Agr & Anim Husb, Linzhi, Peoples R China ; 4 Henan Agr Univ, Coll Anim Husb & Vet Sci, Zhengzhou, Peoples R China ; 5 Huazhong Agr Univ, Key Lab Dev Vet Diagnost Prod, Minist Agr, Coll Vet Med, Wuhan, Peoples R China
【年份】2017
【卷号】Vol.8
【ISSN】1664-3224
【关键词】I-LIKE RECEPTORS NS1 PROTEIN RIG-I INTERFERON-PRODUCTION ANTIVIRAL RESPONSE PATHOGEN RECOGNITION SIGNALING PATHWAY UBIQUITIN LIGASE INNATE IMMUNITY KAPPA-B
【摘要】 Influenza A virus non-structural protein 1 antagonizes interferon response through diverse strategies, particularly by inhibiting the activation of interferon regulatory factor 3 and IFN-beta transcription. However, the underlying mechanisms used b...
【文献类型】期刊