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Serum regulates adipogenesis of mesenchymal stem cells via MEK/ERK-dependent PPARγ expression and phosphorylation

  • 【作者】Ling Wu,Xiaoxiao Cai,Hai Dong,Wei Jing,Yuanding Huang,Xingmei Yang,Yao Wu,Yunfeng Lin
  • 【DOI】10.1111/j.1582-4934.2009.00709.x
  • 【作者单位】a State Key Laboratory of Oral Diseases, West China College of Stomatology, Sichuan University, Chengdu, P. R. China b Department of Tissue Regeneration, Institute for Biomedical Technology, University of Twente, Enschede, The Netherlands c Dental Implant Center, West China College of Stomatology, Sichuan University, Chengdu, P.R. China d Department of Stomatology, Medical College, Tibet University, Lhasa, P. R. China
  • 【年份】2010
  • 【卷号】Vol.14 No.4
  • 【页码】922-932
  • 【ISSN】1582-1838
  • 【关键词】peroxisome proliferator–activated receptor γ mesenchymal stem cells adipogenesis mitogen-activated protein kinase extracellular signal-regulated kinase 
  • 【摘要】 Mesenchymal stem cells (MSCs) provide us an excellent cellular model to uncover the molecular mechanisms underlying adipogenic differentiation of adult stem cells. PPARγ had been considered as an important molecular marker of cells undergoing adipoge...
  • 【文献类型】 期刊
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