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Screening and identification of α-glucosidase inhibitors from Cyclocarya paliurus leaves by ultrafiltration coupled with liquid chromatography-mass spectrometry and molecular docking

  • 【作者】Yan-Jun Li,Guang-Zhen Wan,Fu-Chun Xu,Zhao-Hui Guo,Juan Chen
  • 【作者单位】1 School of Pharmacy, Lanzhou University, Lanzhou 730000, P. R. China; 2 Innovation Center for Traditional Tibetan Medicine Modernization and Quality Control, Medical College, Tibet University, Lhasa 850000, P. R. China; 3 Gansu Institute for Drug Control, Lanzhou 730000, P. R. China; 4 State Drug Administration-Key Laboratory of Quality Control of Chinese Medicinal Materials and Decoction Pieces, Lanzhou 730000, P. R. China; 5 Gansu Engineering Technology Laboratory for Inspection and Testing of Chinese and Tibetan Medicine, Lanzhou, P. R. China
  • 【年份】2022
  • 【页码】463160
  • 【ISSN】0021-9673
  • 【关键词】Cyclocarya paliurus leaves α-Glucosidase inhibitors Ultrafiltration UPLC-QTOF-MS/MS Molecular docking 
  • 【摘要】 Cyclocarya paliurus, as an important edible and medicinal product, has shown a good prospect in the prevention of diabetes mellitus . However, it is unclear which active compounds derived from C. paliurus play a significant role in inhibiting α-gluco...
  • 【文献类型】 期刊
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