Screening and identification of α-glucosidase inhibitors from Cyclocarya paliurus leaves by ultrafiltration coupled with liquid chromatography-mass spectrometry and molecular docking
【作者】Yan-Jun Li, Guang-Zhen Wan, Fu-Chun Xu, Zhao-Hui Guo, Juan Chen
【作者单位】Affiliations 1 School of Pharmacy, Lanzhou University, Lanzhou 730000, PR China. 2 School of Pharmacy, Lanzhou University, Lanzhou 730000, PR China; Innovation Center for Traditional Tibetan Medicine Modernization and Quality Control, Medical College, Tibet University, Lhasa 850000, PR China. 3 Gansu Institute for Drug Control, Lanzhou 730000, PR China; State Drug Administration-Key Laboratory of Quality Control of Chinese Medicinal Materials and Decoction Pieces, Lanzhou 730000, PR China; Gansu Engineering Technology Laboratory for Inspection and Testing of Chinese and Tibetan Medicine, Lanzhou, PR China. Electronic address: 1282664933@qq.com. 4 School of Pharmacy, Lanzhou University, Lanzhou 730000, PR China. Electronic address: chenjuan@lzu.edu.cn.
【摘要】 Cyclocarya paliurus, as an important edible and medicinal product, has shown a good prospect in the prevention of diabetes mellitus . However, it is unclear which active compounds derived from C. paliurus play a significant role in inhibiting α-gluco...