【作者单位】1Taikang Medical School (School of Basic Medical Sciences), Wuhan University, Wuhan 430071, P.R. China;;2These authors contributed equally to this work: Sen Yuan, Jiaqi Xu, Min Wang;3Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan 430072, P.R. China;;4Department of Hepatic & Biliary & Pancreatic Surgery, Hubei Cancer Hospital, Affiliated Hubei Cancer Hospital of Huazhong University of Science and Technology, 116 Zhuodaoquan South Road, Wuhan 430079, P.R. China;;5School of Medicine, Sun Yat-Sen University, Guangdong, P.R. China;;6Ecological Research Center, College of Science, Tibet University, Lhasa 850012, P.R. China;;7State Key Laboratory of Virology, Hubei Provincial Key Laboratory of Allergy and Immunology, Wuhan 430071, P.R. China
【摘要】 Chronic hepatitis B virus infection is a leading cause of hepatocellular carcinoma . However, the function and mechanism of the effect of HBV on host protein ubiquitination remains largely unknown. We aimed at characterizing if and how HBV promotes ...